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Sunday, June 5, 2011

Breast cancer treatment must not go to the extreme

An average of about 140 million people worldwide each year with breast cancer, more than 20 of each year a million women suffering from breast cancer. As a threat to women's health, "the number one killer" of breast cancer in China are up in morbidity and mortality trends.

Representative of the female breast beautiful and unique, but this "chest landscape" but also make women carry more risk. An average of about 140 million people worldwide each year with breast cancer, my more than 20 million women each year with breast cancer. As a threat to women's health, "the number one killer" of breast cancer in China are up in morbidity and mortality trends. According to China Population Association recently published "Chinese breast disease survey report," China's urban growth in the breast cancer mortality 38.91%. Ministry of Health has breast cancer prevention in China as one of the key.

After diagnosis of breast cancer, early treatment of active norms, and based on individual characteristics of 'custom' of effective treatment options that can achieve high cure rate, Implementation and breast cancer 'peaceful coexistence'. Refrain from treatment because of various concerns, or listen to rumors refuse to random drug, not only delayed their condition and may cause disease progression or recurrence, to themselves and their families are enormous economic and psychological burden.

Healthy women: breast cancer prevention can not rely on "self"

Breast cancer is terrible, which many people mistakenly think the only symptom is breast cancer appear or soft or hard mass. How good, to suffer from breast cancer hyperplasia that this is it? Many "patients" to issue such a question. Experts point out that breast hyperplasia is a common benign, the possibility of cancer is very small, not nervous. Since changes in the environment, work pressure, life changing and so are the reasons for female breast hyperplasia. But 90% of breast hyperplasia is safe, not cancer, but women friends also do not, for whatever reason neglected the health of the breast.

Life, many women believe that self-examination can prevent cancer, they would rather spend thousands of dollars to do beauty treatments cost less than a hundred dollars for breast cancer detection but "you could save on the province", which is a must be corrected errors. Although self-examination is very important, but many no clinical signs of early breast cancer and can not self-discovery. As early as 2005, the United States in the early diagnosis guidelines no longer recommend this method already.

A variety of reasons, many women have not received a formal life of breast examination. Age women in the mass has not yet formed the best breast cancer prevention plan prior to implementation, not passively waiting for doctors to give inspection advice, suggestions:

For women without breast cancer risk factors: 40 years of age or women can use color Doppler ultrasound examination methods such as regular inspection, because the women in this age of high breast density, mammography X ray is difficult to penetrate, observation is unclear, the effect is discounted . 40-50 years old under the guidance of a doctor to do during the mammography X-ray examination once a year over 50 years old X-ray mammography.

High risk for breast cancer, such as age of menarche is less than 12 years of age or menopausal age older than 55 years of age, first child bearing age over 35 or childbirth, postpartum who are not breast-feeding, family history of breast cancer patients who, it is recommended medical advice on a regular basis while breast X-ray examination, combined with monthly self-examination and regular clinical examination.

Once a mass, must be diagnosed as soon as possible, need to identify the tumor was benign or malignant, doctors often advise patients to biopsy. When the tumor occurs in the lungs, liver and other organs deep entities, the need for biopsy. However, many patients worry that this examination is painful, so afraid to even refused biopsy. There is no sufficient evidence that the biopsy will lead to disease progression. And the United States for examination and treatment of breast cancer, is still insisting on 90% of patients with biopsy.

Breast cancer: early diagnosis, the cure rate of up to 95%

According to the World Health Organization, breast cancer is through early diagnosis and early treatment of cancer mortality. If diagnosed early, the cure rate of up to 95%. However, as the "cancer" the fear of people deeply rooted in traditional values, so most people think that "cancer is a terminal illness," many patients do not even have confirmed the confidence of the treatment.

Some of "mother" to check the baby in my arms on breast cancer, fear of the treatment will affect the fetus refuse treatment, and finally almost led to "a funeral of two lives," the tragedy. And some found themselves having lumps in the breast older women, although it had a premonition that may be cancer, but considering the heavy burden to their children, so hard to endure cancer pain.

Experts Call for the majority of female friends: Do not hide exceptions refused medical treatment, such as early diagnosis of breast cancer, timely surgery can return to society as well as ordinary people to work more than ten years survival rate is also high, spend most provinces. Do not use while some content is not clear, the mechanism is not clear, the health care component is not clear to therapy because it may contain do not know which ingredients will accelerate tumor progression.

Menopause: treatment programs need to "custom"

Is also a breast cancer, clinical disease often appear the same but the treatment response seems quite different situation. In fact, breast cancer is not a single disease, according to the actual condition of the special circumstances, for patients 'customized' treatment.

For many patients still young, require a higher quality of life and future demand growth there, the doctor will try to retain ovarian function, usually this type of tamoxifen, a drug used for treatment. The endocrine treatment of postmenopausal breast cancer, the main drug used is such as exemestane has a higher selectivity and tolerability of aromatase inhibitors, by interfering with the effects of aromatase and estrogen production, thus reducing the arrival the amount of estrogen in breast cancer cells in preventing tumor progression and mitigation of the effect of better breast cancer treatment drug development is the trend.

So far that the best endocrine treatment of breast cancer after 5 years, the make 5-year recurrence rate and mortality rate decreased by 50% and 26%, but only received 2 years of endocrine therapy in patients with only decreased the risk of tumor recurrence 28%. Therefore, estrogen and progesterone receptor-positive breast cancer patients, after receiving adequate attention must be courses of endocrine therapy to reduce tumor recurrence or metastasis. If a patient receiving treatment at the beginning of menopause yet, you can choose to use tamoxifen treatment, 5 years of endocrine therapy in the course of menopause, can adjust the program according to the situation in a timely manner, replaced with better aromatase inhibitors.

Breast cancer is not terrible, in fact, the fate of patients in their own hands. How early after surgery and standard endocrine therapy is the key to preventing relapse. Majority of female friends in time to prevent the invasion of breast cancer, and breast cancer patients should actively address the disease, to regulate the endocrine therapy as soon as possible, hold for 1-5 years after surgery the treatment of critical period, bid goodbye to relapse, do not suffer in silence or listen to " rivers and lakes Youyi "wasted the best time to get the best treatment.

Tips for endocrine therapy in breast cancer:

1, endocrine therapy has no side effects? Have any side effects

Drugs have some side effects. Side effects of tamoxifen are hot flushes, vaginal discharge, also after some patients took tamoxifen liver function can cause some damage. But the most worthy of our concern is that sometimes after using tamoxifen cause endometrial hyperplasia, have also been reported in endometrial hyperplasia and endometrial cancer after the formation of the possibility of more. Side effects of aromatase inhibitors is mainly due to its inhibition of estrogen within the body after the application process may appear the main side effects is muscle pain, joint pain or bone loss due to calcium deficiency, and so the situation . Of course people use the process, cholesterol and so may be some side effects, but this is rare.

2, the use of aromatase inhibitors after the lumbar and leg pain, can not stand for long periods and travel how to do

Postmenopausal breast cancer patients already prone to the problem of osteoporosis, the use of aromatase inhibitors will exacerbate this situation. Proposed assessment of bone mineral density in patients less than -2.5, choose different levels at different stages of anti-osteoporosis treatment, if necessary, you can use bisphosphonates to prevent bone loss.

3, breast cancer patients receiving endocrine treatment should pay attention to what

Although a clear effect of endocrine therapy, toxic side effects, treatment quality of life of patients in high, but not free to use, should follow the doctor's guidance, the proper use of a reasonable dose. Once you begin treatment, should adhere to in the end, can not give up halfway, or may lose the best treatment time of treatment. Periodic review to evaluate the therapeutic effect is very important to any course of treatment does not appear, the report should be a doctor in a timely manner. Careful observation of response to endocrine therapy, careful evaluation of the effect of endocrine therapy. Endocrine therapy alone, not unprincipled, unplanned reactor together with the use of chemotherapy.

4, breast cancer and estrogen have anything to do

Study found that breast cancer cells with estrogen has a lot to the continuous stimulation, can promote tumor growth and spread. Therefore, to reduce or block estrogen's effect on tumor regression to the effective and reduce the metastasis and recurrence of tumor. Most premenopausal women estrogen in vivo are derived from the ovary, it is to keep women "feminine," the main source. For postmenopausal women, the ovaries no longer produce estrogen, the body by a substance called aromatase effect on other hormones to produce estrogen. Endocrine therapy is hormone-sensitive breast cancer patients, by reducing estrogen levels or block in patients with estrogen to prevent the recurrence of the tumor to reach a drug treatment.


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